LEED Student WIPs

Welcome to our Works in Progress page – a hub of academic exploration and intellectual endeavor! The posters we’ve described are snapshots of the rigorous work and thought-provoking research currently in development.

For more information, and to view the posters we presented, we encourage you to click on the “Poster” buttons.

FLUX 2024

Effects of Maternal Childhood Maltreatment Exposure on White Matter Integrity in Young Children

Objective

To assess the effects of maternal childhood trauma on offspring white matter.

Methods

MRI (DTI), parent report of childhood maltreatment exposure.

Results

Our results suggest that there may be an intergenerational adaptation for individuals who are forced to develop coping mechanisms to navigate challenging environments. As a result, there is an accelerated development in certain areas, such as neural circuits involved in emotional and stress processing, to cope more effectively with adverse circumstances. Our findings also reveal less efficient development in circuitries that support higher cognitive abilities.

The Influence of Perinatal and Concurrent Risk has on Cognition when Experienced during Sensitive Periods of Development

Hypothesis

We hypothesize that perinatatal risk factors and early childhood socioeconomic risk will have a differential impact on children’s cognitive abilities, specifically domains related to verbal comprehension and visuospatial skills.

Methods

Visuospatial and verbal comprehension tasks (WPPSI); parent self-reports on substance use, pregnancy complications, income, and birth outcomes; child opportunity index.

Results

Our findings indicate that greater socioeconomic risk is associated with poorer child cognitive outcomes compared to perinatal risk exposure. Our findings also demonstrate that the level of deprivation in a child’s environment was associated with visuospatial outcomes over and above other proxies of socioeconomic risk, indicating that early childhood socioeconomic deprivation may have a stronger impact on children’s visuospatial development.

Exploring Effects of Family Resources on Amygdala Resting-State Functional Connectivity in Early Childhood

Objective

To assess the effects of maternal childhood trauma on offspring white matter.

Methods

MRI (DTI), parent report of childhood maltreatment exposure.

Results

Our results suggest that there may be an intergenerational adaptation for individuals who are forced to develop coping mechanisms to navigate challenging environments. As a result, there is an accelerated development in certain areas, such as neural circuits involved in emotional and stress processing, to cope more effectively with adverse circumstances. Our findings also reveal less efficient development in circuitries that support higher cognitive abilities.

FIT'NG 2024

Neural Indicators of Visual Attention in Premature Toddlers

Goal

Investigate the neural basis of visual attention development in toddlers born prematurely to better understand behavioral risk

Methods

Toddlers engaged in a sustained attention task while using EEG recording. Sustained attention is captured by quantifying the proportion of looking behavior in association with the stimulus.

Results

In summary, both behavioral measures and alpha power exhibited similar development trajectories across age in the preterm group. These findings suggest that earlier gestational ages may be associated with altered neural developmental trajectories in visual attention.

Flux 2023; Santa Rosa, CA

Associations between Socioemotional Neural Responses and Behavioral Outcomes in Toddlers Born Preterm

Hypotheses

Toddlers born with more severe levels of prematurity would exhibit poorer brain function as presented by ERPs.
Toddler's brain function would be associated with externalizing problems as measured by a behavioral task.

Methods

Dynamic facial expression task, behavioral assessment (tool task), EEG

Results

Our results indicate that toddlers with different severity levels of prematurity did not show differences in their ERPs. Our findings suggest that there is a significant association between Nc amplitude and child externalizing problems, represented by noncompliance, supporting our second hypothesis.

The Impact of Varying Dimensions of Adversity on the Neurofunction of Working Memory in Early Childhood

Goal

We aim to examine the relations of adverse experiences related to caregiving and distal risk to the neurofunction of visuospatial WM in early childhood.

Methods

Visuospatial working memory task, caregiver mental health composite, distal factors composite, fNIRS

Results

Our findings suggest that environmental risk and caregiver mental health have a differential impact on the neurofunctional activity of WM.

Integrating Dimensional Models of Early Adversity: Relative Contributions of Caregiver and Environmental Risks on Frontal-Limbic Development in Early Childhood

Hypothesis

We hypothesize that experiences of adversity in the caregiving context, such as parent psychopathology or family involvement with Child Protective Services (CPS) will be uniquely associated with brain development, over and above environmental stressors, such as economic and community resources.

Methods

Caregiving risk composite, family CPS involvement, environmental risk composite, MRI

Results

Our hypotheses were partially supported, finding caregiving related risk was consistently associated with neurodevelopment, compared to environmental factors.

SRCD 2023; Salt Lake City, UT

Exploring Associations between Stress Exposures, Parenting, and Psychopathology

Hypothesis

We hypothesize that parenting practices will have a greater influence on psychopathology symptoms for younger youth. We also hypothesize that negative parenting will exacerbate risk for psychopathology in the presence of increased contextual stressors and positive parenting will serve as a protective factor.

Methods

Pubertal status, contextual stressors, youth psychopathology, parenting practices

Results

Contrary to our hypotheses, we did not find significant effects examining associations between parenting, stressors, and psychopathology in pre- and post-puberty groups.

FLUX 2022; Paris, France

Differences in the Neural Processing of Dynamic Expressions in Toddlers Born Preterm

Hypotheses

There would be a larger neural response to angry face/threat.
There would be a difference in neural response between children born very preterm and extreme preterm.

Methods

Dynamic facial expression task, EEG

Results

Our results indicate that toddlers born preterm are more sensitive to angry facial expressions than to happy and neutral expressions, given that larger amplitude of Nc reflects greater allocation of attention to threat, supporting our hypothesis I. Our study did not find differences in neural response between toddlers born extremely preterm and very preterm.

ISDP 2022; San Diego, CA

Parasympathetic Regulation during Executive Function Tasks and Behavioral Outcomes among Low SES Children

Goals

Examine separate physiological variability during cool and hot EF from baseline.
Examine the relationship between physiological variability and performance on EF tasks.
Elucidate associations of physiological regulation during cognitive tasks on child internalizing and externalizing outcomes.

Methods

Internalizing and externalizing symptoms (BASC), executive function tabletop tasks, RSA

Results

Findings indicate a nuanced relationship between risk for psychopathology, self-regulatory abilities, and cognitive control, such that physiological variability exists during the type of EF elicited (i.e., cool versus hot) during cognitive challenges

SRCD 2021; Virtual

Associations between Perceived Family Resources and Cortical Morphology in Young Children with Varying SES

Hypothesis

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Methods

Household information (size and INR), Family Resource Scale, MRI

Results

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ISDP 2020; Virtual

Links between Maternal Distress, Brain Function, and Working Memory in Early Childhood

Hypothesis

We hypothesized maternal depression and anxiety were associated with child brain function in the context of working memory (WM).

Methods

Maternal depression and anxiety (BDI, STAI), child executive functioning (BRIEF), visuospatial working memory task, fNIRS

Results

Our results indicate that young children exposed to greater maternal depression and anxiety exhibited lower brain activation in prefrontal regions. Variability in LPFC activation was associated with risk for poor executive functioning in early childhood.